Lower blood return temperature than core temperature as a causal factor of decreased cardiac output assessed by transpulmonary thermodilution during blood purification

Tomoyuki Nakamura, Takahiro Kawaji, Tatsuhiko Harada, Yu Kato, Kazuhiro Moriyama, Daisuke Hasegawa, Hidefumi Komura, Junpei Shibata, Chizuru Yamashita, Naohide Kuriyama, Yoshitaka Hara, Osamu Nishida

Research output: Contribution to journalArticlepeer-review

Abstract

We aimed to evaluate whether cardiac output assessed by transpulmonary thermodilution during blood purification is affected by the difference between the blood return temperature and core temperature. We applied different blood return temperatures using a thermostat bath during blood purification in four pigs. After the blood return temperature stabilized and blood purification process stopped, the cardiac output assessed by transpulmonary thermodilution was measured. The thermostat bath was set at 35°C, 40°C, 45°C, and 50°C, with the order changed at random; four measurements were made at each temperature. Cardiac function was evaluated by echocardiography when ice-cold saline was administered in a pig. A decrease in the blood return temperature resulted in decreased cardiac output assessed by transpulmonary thermodilution, whereas an increase resulted in increased cardiac output assessed by transpulmonary thermodilution. Echocardiography revealed that the change in the blood return temperature did not affect the left ventricular ejection fraction.

Original languageEnglish
Pages (from-to)476-481
Number of pages6
JournalTherapeutic Apheresis and Dialysis
Volume24
Issue number5
DOIs
StatePublished - 1 Oct 2020
Externally publishedYes

Keywords

  • cardiac output
  • extracorporeal circulation
  • hemodynamic monitoring
  • renal replacement therapy
  • thermodilution

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