TY - JOUR
T1 - Lower Blood Pressure and Apathy Coincide in Older Persons with Poorer Functional Ability
T2 - The Discontinuation of Antihypertensive Treatment in Elderly People (DANTE) Study Leiden
AU - Moonen, Justine E.F.
AU - Bertens, Anne Suzanne
AU - Foster-Dingley, Jessica C.
AU - Smit, Roelof A.J.
AU - van der Grond, Jeroen
AU - de Craen, Anton J.M.
AU - de Ruijter, Wouter
AU - van der Mast, Roos C.
N1 - Publisher Copyright:
© 2015, Copyright the Authors Journal compilation © 2015, The American Geriatrics Society
PY - 2015/1/1
Y1 - 2015/1/1
N2 - Objectives: To examine the association between blood pressure (BP) measures and symptoms of apathy and depression in older adults with various levels of functional ability. Design: Cross-sectional study using baseline data from the Discontinuation of Antihypertensive Treatment in Elderly people (DANTE) Study Leiden. Setting: Primary care setting, the Netherlands. Participants: Community-dwelling individuals aged 75 and older (N = 430). Measurements: Systolic BP (SBP), diastolic BP (DBP), and mean arterial pressure (MAP) were measured during home visits. Symptoms of apathy and depression were assessed using the Apathy Scale and the Geriatric Depression Scale (GDS-15), respectively. Stratified linear regression was performed in participants with better and worse functional ability according to the median of the Groningen Activity Restriction Scale. Results: In participants with lower functional ability, each 10-mmHg lower SBP, DBP, and MAP was associated with higher Apathy Scale scores (0.63, 0.92, and 0.94 points, respectively, all P <.005) but not with GDS-15 scores. In participants with higher functional ability, BP measures were not associated with Apathy Scale or GDS-15 scores. Conclusion: In older participants with poorer functional ability, lower BP was associated with more symptoms of apathy but not depression.
AB - Objectives: To examine the association between blood pressure (BP) measures and symptoms of apathy and depression in older adults with various levels of functional ability. Design: Cross-sectional study using baseline data from the Discontinuation of Antihypertensive Treatment in Elderly people (DANTE) Study Leiden. Setting: Primary care setting, the Netherlands. Participants: Community-dwelling individuals aged 75 and older (N = 430). Measurements: Systolic BP (SBP), diastolic BP (DBP), and mean arterial pressure (MAP) were measured during home visits. Symptoms of apathy and depression were assessed using the Apathy Scale and the Geriatric Depression Scale (GDS-15), respectively. Stratified linear regression was performed in participants with better and worse functional ability according to the median of the Groningen Activity Restriction Scale. Results: In participants with lower functional ability, each 10-mmHg lower SBP, DBP, and MAP was associated with higher Apathy Scale scores (0.63, 0.92, and 0.94 points, respectively, all P <.005) but not with GDS-15 scores. In participants with higher functional ability, BP measures were not associated with Apathy Scale or GDS-15 scores. Conclusion: In older participants with poorer functional ability, lower BP was associated with more symptoms of apathy but not depression.
KW - apathy
KW - blood pressure
KW - functional ability
KW - older persons
UR - http://www.scopus.com/inward/record.url?scp=85007271108&partnerID=8YFLogxK
U2 - 10.1111/jgs.13199
DO - 10.1111/jgs.13199
M3 - Article
AN - SCOPUS:85007271108
SN - 0002-8614
VL - 63
SP - 112
EP - 117
JO - Journal of the American Geriatrics Society
JF - Journal of the American Geriatrics Society
IS - 1
ER -