Low platelet monoamine oxidase activity in borderline personality disorder

Rachel Yehuda; Steven M. Southwick; William S. Edell; Earl L. Giller

doi:10.1016/0165-1781(89)90018-8

Low platelet monoamine oxidase activity in borderline personality disorder

Rachel Yehuda
, Steven M. Southwick
, William S. Edell
, Earl L. Giller

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Platelet monoamine oxidase (MAO) activity was significantly lower in nonpsychotic, nonorganic, unmedicated male inpatients with DSM-III-R borderline personality disorder (BPD) than in nonpsychiatric controls. Patients with BPD who also met DSM-III-R criteria for antisocial personality disorder had significantly lower MAO activity than those with BPD alone. Low MAO activity in this sample did not appear to be related to the comoroid presence of major depressive disorder or a history of substance abuse.

Original language	English
Pages (from-to)	265-273
Number of pages	9
Journal	Psychiatry Research
Volume	30
Issue number	3
DOIs	https://doi.org/10.1016/0165-1781(89)90018-8
State	Published - Dec 1989
Externally published	Yes

Keywords

Platelet monoamine oxidase activity
antisocial personality disorder
borderline personality disorder
major depressive disorder
substance abuse

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10.1016/0165-1781(89)90018-8

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title = "Low platelet monoamine oxidase activity in borderline personality disorder",

abstract = "Platelet monoamine oxidase (MAO) activity was significantly lower in nonpsychotic, nonorganic, unmedicated male inpatients with DSM-III-R borderline personality disorder (BPD) than in nonpsychiatric controls. Patients with BPD who also met DSM-III-R criteria for antisocial personality disorder had significantly lower MAO activity than those with BPD alone. Low MAO activity in this sample did not appear to be related to the comoroid presence of major depressive disorder or a history of substance abuse.",

keywords = "Platelet monoamine oxidase activity, antisocial personality disorder, borderline personality disorder, major depressive disorder, substance abuse",

author = "Rachel Yehuda and Southwick, \{Steven M.\} and Edell, \{William S.\} and Giller, \{Earl L.\}",

note = "Funding Information: Acknowledgments. Support for this research was provided by Veterans Administration Research Funds and National Institute of Mental Health postdoctoral-training grant S-T32-MH-17122 (R.Y.).",

year = "1989",

month = dec,

doi = "10.1016/0165-1781(89)90018-8",

language = "English",

volume = "30",

pages = "265--273",

journal = "Psychiatry Research",

issn = "0165-1781",

publisher = "Elsevier Ireland Ltd",

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TY - JOUR

T1 - Low platelet monoamine oxidase activity in borderline personality disorder

AU - Yehuda, Rachel

AU - Southwick, Steven M.

AU - Edell, William S.

AU - Giller, Earl L.

N1 - Funding Information: Acknowledgments. Support for this research was provided by Veterans Administration Research Funds and National Institute of Mental Health postdoctoral-training grant S-T32-MH-17122 (R.Y.).

PY - 1989/12

Y1 - 1989/12

N2 - Platelet monoamine oxidase (MAO) activity was significantly lower in nonpsychotic, nonorganic, unmedicated male inpatients with DSM-III-R borderline personality disorder (BPD) than in nonpsychiatric controls. Patients with BPD who also met DSM-III-R criteria for antisocial personality disorder had significantly lower MAO activity than those with BPD alone. Low MAO activity in this sample did not appear to be related to the comoroid presence of major depressive disorder or a history of substance abuse.

AB - Platelet monoamine oxidase (MAO) activity was significantly lower in nonpsychotic, nonorganic, unmedicated male inpatients with DSM-III-R borderline personality disorder (BPD) than in nonpsychiatric controls. Patients with BPD who also met DSM-III-R criteria for antisocial personality disorder had significantly lower MAO activity than those with BPD alone. Low MAO activity in this sample did not appear to be related to the comoroid presence of major depressive disorder or a history of substance abuse.

KW - Platelet monoamine oxidase activity

KW - antisocial personality disorder

KW - borderline personality disorder

KW - major depressive disorder

KW - substance abuse

UR - https://www.scopus.com/pages/publications/0024789173

U2 - 10.1016/0165-1781(89)90018-8

DO - 10.1016/0165-1781(89)90018-8

M3 - Article

C2 - 2616692

AN - SCOPUS:0024789173

SN - 0165-1781

VL - 30

SP - 265

EP - 273

JO - Psychiatry Research

JF - Psychiatry Research

IS - 3

ER -

Low platelet monoamine oxidase activity in borderline personality disorder

Abstract

Keywords

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