Low plasma cholesterol levels in suicidal males: A gender- and body mass index-matched case-control study of suicide attempters and nonattempters

Carmen Diaz-Sastre, Enrique Baca-Garcia, Maria M. Perez-Rodriguez, Eloy Garcia-Resa, Antonio Ceverino, Jeronimo Saiz-Ruiz, Maria A. Oquendo, Jose de Leon

Research output: Contribution to journalArticlepeer-review

56 Scopus citations

Abstract

Findings from animal and human studies suggest an association between low cholesterol levels and suicidal behaviors. The purpose of this case-control study was to test whether cholesterol levels in suicide attempters are lower than in controls without suicide attempt history matched by gender, age, and body mass index (BMI). Suicide attempters (n = 177: 68 men and 109 women) and controls (177 blood donors) were assessed. Serum cholesterol levels were significantly lower in suicide attempters than in controls. After gender stratification, the difference remained significant in men, but not in women.

Original languageEnglish
Pages (from-to)901-905
Number of pages5
JournalProgress in Neuro-Psychopharmacology and Biological Psychiatry
Volume31
Issue number4
DOIs
StatePublished - 9 May 2007
Externally publishedYes

Keywords

  • Aggressiveness
  • Cholesterol
  • Impulsivity
  • Serotonin
  • Suicide

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