Low level expression of basic FGF upregulates Bcl-2 and delays apoptosis, but high intracellular levels are required to induce transformation in NIHW 3T3 cells

Robert Wieder; Huisheng Wang; Sanjay Shirke; Qin Wang; Thomas Menzel; Nikki Feirt; Ann A. Jakubowski; Janice L. Gabrilove

doi:10.3109/08977199709002111

Low level expression of basic FGF upregulates Bcl-2 and delays apoptosis, but high intracellular levels are required to induce transformation in NIHW 3T3 cells

Robert Wieder
, Huisheng Wang
, Sanjay Shirke
, Qin Wang
, Thomas Menzel
, Nikki Feirt
, Ann A. Jakubowski
, Janice L. Gabrilove

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

Original language	English
Pages (from-to)	41-60
Number of pages	20
Journal	Growth Factors
Volume	15
Issue number	1
DOIs	https://doi.org/10.3109/08977199709002111
State	Published - 1997
Externally published	Yes

Keywords

Apoptosis
Bax
Bcl-2
FGF
Retroviral vectors
Transformation

Access to Document

10.3109/08977199709002111

Cite this

@article{4d1a3a2f339f425984cf144298b0b429,

title = "Low level expression of basic FGF upregulates Bcl-2 and delays apoptosis, but high intracellular levels are required to induce transformation in NIHW 3T3 cells",

keywords = "Apoptosis, Bax, Bcl-2, FGF, Retroviral vectors, Transformation",

author = "Robert Wieder and Huisheng Wang and Sanjay Shirke and Qin Wang and Thomas Menzel and Nikki Feirt and Jakubowski, \{Ann A.\} and Gabrilove, \{Janice L.\}",

year = "1997",

doi = "10.3109/08977199709002111",

language = "English",

volume = "15",

pages = "41--60",

journal = "Growth Factors",

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publisher = "Taylor and Francis Ltd.",

number = "1",

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T1 - Low level expression of basic FGF upregulates Bcl-2 and delays apoptosis, but high intracellular levels are required to induce transformation in NIHW 3T3 cells

AU - Wieder, Robert

AU - Wang, Huisheng

AU - Shirke, Sanjay

AU - Wang, Qin

AU - Menzel, Thomas

AU - Feirt, Nikki

AU - Jakubowski, Ann A.

AU - Gabrilove, Janice L.

PY - 1997

Y1 - 1997

KW - Apoptosis

KW - Bax

KW - Bcl-2

KW - FGF

KW - Retroviral vectors

KW - Transformation

UR - https://www.scopus.com/pages/publications/0343307095

U2 - 10.3109/08977199709002111

DO - 10.3109/08977199709002111

M3 - Article

C2 - 9401817

AN - SCOPUS:0343307095

SN - 0897-7194

VL - 15

SP - 41

EP - 60

JO - Growth Factors

JF - Growth Factors

IS - 1

ER -