Low-Dose Epinephrine: Effect on Intraocular Pressure

Stephen A. Obstbaum, Allan E. Kolker, Charles D. Phelps

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


The effect of low doses of epinephrine hydrochloride on intraocular pressure was evaluated. Concentrations of ⅛%, ¼%, ½% and 1% epinephrine were administered to one eye of a patient over a four-week period. An interval of four weeks was allowed before the successive higher concentration was applied. The fellow eye was left untreated and served as a control. The results indicate that epinephrine lowers intraocular pressure at the concentrations tested with significantly greater effectiveness at the higher dose levels.

Original languageEnglish
Pages (from-to)118-120
Number of pages3
JournalArchives of Ophthalmology
Issue number2
StatePublished - Aug 1974
Externally publishedYes


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