Abstract
In earlier studies, the authors showed that healing arteries in rabbits and atherosclerotic arteries in humans sequestered radiolabeled low density lipoproteins (LDL), the major cholesterol-carrying proteins of human plasma. The focal accumulation of radiolabeled LDL permitted external imaging of the affected arteries. Since arterial grafts provoke a healing response analogous in many respects to native arterial intimal repair, the authors tested the possibility that healing prosthetic vascular grafts might also accumulate radiolabeled LDL. This paper reports preliminary studies of the sequestration of LDL by arterial grafts in the rabbit and the potential significance of the finding for monitoring graft function and preducing graft failure.
| Original language | English |
|---|---|
| Pages (from-to) | 489-493 |
| Number of pages | 5 |
| Journal | ASAIO Transactions |
| Volume | 33 |
| Issue number | 3 |
| State | Published - Jul 1987 |