LOW DENSITY LIPOPROTEIN ACCUMULATION BY PTFE GRAFTS IN THE RABBIT AORTA: AUTORADIOGRAPHIC-MORPHOLOGIC CORRELATIONS.

Arnold Miller, Frederick J. Schoen, Ann M. Lees, John T. Fallon, H. William Strauss, Robert S. Lees

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

In earlier studies, the authors showed that healing arteries in rabbits and atherosclerotic arteries in humans sequestered radiolabeled low density lipoproteins (LDL), the major cholesterol-carrying proteins of human plasma. The focal accumulation of radiolabeled LDL permitted external imaging of the affected arteries. Since arterial grafts provoke a healing response analogous in many respects to native arterial intimal repair, the authors tested the possibility that healing prosthetic vascular grafts might also accumulate radiolabeled LDL. This paper reports preliminary studies of the sequestration of LDL by arterial grafts in the rabbit and the potential significance of the finding for monitoring graft function and preducing graft failure.

Original languageEnglish
Pages (from-to)489-493
Number of pages5
JournalASAIO Transactions
Volume33
Issue number3
StatePublished - Jul 1987

Fingerprint

Dive into the research topics of 'LOW DENSITY LIPOPROTEIN ACCUMULATION BY PTFE GRAFTS IN THE RABBIT AORTA: AUTORADIOGRAPHIC-MORPHOLOGIC CORRELATIONS.'. Together they form a unique fingerprint.

Cite this