Loss of MMP-2 in murine osteoblasts upregulates osteopontin and bone sialoprotein expression in a circuit regulating bone homeostasis

Biochemistry, Genetics and Molecular Biology

• Homeostasis 100%
• Osteoblast 100%
• Gelatinase A 100%
• MMP2 100%
• Osteopontin 100%
• Bone Sialoprotein 100%
• Mouse 42%
• Osteolysis 42%
• Western Blot 28%
• Small Interfering RNA 28%
• Quantitative Reverse Transcription Polymerase Chain Reaction 28%
• Stromal Cell 28%
• Upregulation 14%
• RNA 14%
• Gene Expression 14%
• Cell Culture 14%
• Dysplasia 14%
• Blood Level 14%

Keyphrases

• Matrix metalloproteinase-2 (MMP-2) 100%
• Osteopontin 100%
• Osteoblast 100%
• Bone Homeostasis 100%
• Bone Sialoprotein 100%
• Osteolysis 25%
• Western Blot 16%
• Small Interfering RNA (siRNA) 16%
• Human Mesenchymal Stem Cells (hMSCs) 16%
• Multicentric 16%
• Quantitative RT-PCR 16%
• Arthropathy 16%
• Gene Expression 8%
• Protein Level 8%
• MRNA Level 8%
• Expression Level 8%
• Human Disease 8%
• Cultured Cells 8%
• Human Syndromes 8%
• Serum Levels 8%
• Immunohistochemical Staining 8%
• Molecular Effects 8%
• Circuitry 8%
• Arthritis 8%
• Osteoblast Functions 8%
• Skeletal Dysplasia 8%
• Skeletal Phenotype 8%
• Osteoblast Differentiation 8%
• Matrix Effect 8%
• Skeletal Defects 8%
• Molecular Landscape 8%
• Saos-2 Cells 8%
• Osteogenic Phenotype 8%

Immunology and Microbiology

• Homeostasis 100%
• Osteopontin 100%
• Osteoblast 100%
• Mouse 50%
• Osteolysis 50%
• Western Blot 33%
• Quantitative Reverse Transcription Polymerase Chain Reaction 33%
• Arthropathy 33%
• Upregulation 16%
• Gene Expression 16%
• Cell Culture 16%
• Blood Level 16%
• Arthritis 16%