Abstract
Cultured rat pituitary cells known to synthesize growth hormone were fixed and exposed to antigrowth hormone antibody conjugated to horseradish peroxidase. The cells were then incubated to demonstrate peroxidase activity. Reaction product was present within the endoplasmic reticulum, including the nuclear envelope. Study of several types of control preparations strongly suggests that the antibody binding material in the endoplasmic reticulum is growth hormone.
| Original language | English |
|---|---|
| Pages (from-to) | 385-394 |
| Number of pages | 10 |
| Journal | Journal of Histochemistry and Cytochemistry |
| Volume | 22 |
| Issue number | 6 |
| DOIs | |
| State | Published - 1974 |