Localization of preprogalanin mRNA in the monkey hippocampal formation

Helen F. Evans; George W. Huntley; John H. Morrison; John Shine; George Paxinos

doi:10.1016/0304-3940(92)90070-N

Localization of preprogalanin mRNA in the monkey hippocampal formation

Helen F. Evans, George W. Huntley, John H. Morrison, John Shine, George Paxinos

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

The existence of neurons expressing preprogalanin mRNA in the monkey hippocampal formation was demonstrated using in situ hybridization of a radio-labelled cRNA probe transcribed from human preprogalanin cDNA. Specific hybridization occurred in neurons of the hilus of the dentate gyrus, fields CA1-3 in Ammon's horn, subiculum, presubiculum, parasubiculum and occasionally in neurons of the entorhinal cortex. These findings suggest that galanin is synthesized by neurons intrinsic to the monkey hippocampal formation.

Original language	English
Pages (from-to)	171-175
Number of pages	5
Journal	Neuroscience Letters
Volume	146
Issue number	2
DOIs	https://doi.org/10.1016/0304-3940(92)90070-N
State	Published - 9 Nov 1992

Keywords

Galanin mRNA
Hippocampus
In situ hybridization histochemistry
Monkey
Neuropeptide

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title = "Localization of preprogalanin mRNA in the monkey hippocampal formation",

abstract = "The existence of neurons expressing preprogalanin mRNA in the monkey hippocampal formation was demonstrated using in situ hybridization of a radio-labelled cRNA probe transcribed from human preprogalanin cDNA. Specific hybridization occurred in neurons of the hilus of the dentate gyrus, fields CA1-3 in Ammon's horn, subiculum, presubiculum, parasubiculum and occasionally in neurons of the entorhinal cortex. These findings suggest that galanin is synthesized by neurons intrinsic to the monkey hippocampal formation.",

keywords = "Galanin mRNA, Hippocampus, In situ hybridization histochemistry, Monkey, Neuropeptide",

author = "Evans, {Helen F.} and Huntley, {George W.} and Morrison, {John H.} and John Shine and George Paxinos",

note = "Funding Information: H.E. is a recipient of a National Health and Medical Research Council Biomedical Postgraduate Fellowship. We thank Jim Roberts and Moshe Jakubowski for valuable advice on in situ hybridization and the preparation of RNA.",

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doi = "10.1016/0304-3940(92)90070-N",

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T1 - Localization of preprogalanin mRNA in the monkey hippocampal formation

AU - Evans, Helen F.

AU - Huntley, George W.

AU - Morrison, John H.

AU - Shine, John

AU - Paxinos, George

N1 - Funding Information: H.E. is a recipient of a National Health and Medical Research Council Biomedical Postgraduate Fellowship. We thank Jim Roberts and Moshe Jakubowski for valuable advice on in situ hybridization and the preparation of RNA.

PY - 1992/11/9

Y1 - 1992/11/9

N2 - The existence of neurons expressing preprogalanin mRNA in the monkey hippocampal formation was demonstrated using in situ hybridization of a radio-labelled cRNA probe transcribed from human preprogalanin cDNA. Specific hybridization occurred in neurons of the hilus of the dentate gyrus, fields CA1-3 in Ammon's horn, subiculum, presubiculum, parasubiculum and occasionally in neurons of the entorhinal cortex. These findings suggest that galanin is synthesized by neurons intrinsic to the monkey hippocampal formation.

AB - The existence of neurons expressing preprogalanin mRNA in the monkey hippocampal formation was demonstrated using in situ hybridization of a radio-labelled cRNA probe transcribed from human preprogalanin cDNA. Specific hybridization occurred in neurons of the hilus of the dentate gyrus, fields CA1-3 in Ammon's horn, subiculum, presubiculum, parasubiculum and occasionally in neurons of the entorhinal cortex. These findings suggest that galanin is synthesized by neurons intrinsic to the monkey hippocampal formation.

KW - Galanin mRNA

KW - Hippocampus

KW - In situ hybridization histochemistry

KW - Monkey

KW - Neuropeptide

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DO - 10.1016/0304-3940(92)90070-N

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VL - 146

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JO - Neuroscience Letters

JF - Neuroscience Letters

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ER -

Localization of preprogalanin mRNA in the monkey hippocampal formation

Abstract

Keywords

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