Localised myeloma with osteogenesis and Russell body formation

S. Lipper, L. B. Kahn, N. Hesselson

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

A case of an osteosclerotic myeloma of the mandible is described. Bone formation took the form of prominent sunray spiculation and radiologically mimicked an osteosarcoma. No other well documented solitary lesion of this type could be found in the English literature. In addition, this tumor contained an abundance of intracytoplasmic Russell bodies and also produced a paraprotein. The paraprotein peak disappeared after resection. Eosinophilic hyaline globules similar in appearance to Russell bodies have been described in normal adrenal medulla and liver, in carcinoma cells from the lung, breast and liver, and in lymphoma and leukemia cells. They differ from Russell bodies in that they are negative for phospholipid and ribonucleic acid.

Original languageEnglish
Pages (from-to)2041-2045
Number of pages5
JournalSouth African Medical Journal
Volume49
Issue number49
StatePublished - 1975
Externally publishedYes

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