Lipoprotein-X and Lipoprotein-Z Induced Hyperviscosity Syndrome in the Setting of Cholestatic Liver Failure

Ori Waksman, Daniel J. Cho, Hyoung Sup Kim, James D. Otvos, Robert S. Rosenson

Research output: Contribution to journalArticlepeer-review

Abstract

We describe a case referred for worsening hypercholesterolemia in the setting of atorvastatin and fenofibrate-induced liver injury. The patient reported neurological complaints attributed to hyperviscosity syndrome (induced by lipoprotein-X and lipoprotein-Z). Hepatic recovery was associated with reduction of whole blood viscosity and amelioration of neurological symptoms. (Level of Difficulty: Advanced.)

Original languageEnglish
Pages (from-to)1348-1352
Number of pages5
JournalJACC: Case Reports
Volume4
Issue number20
DOIs
StatePublished - 19 Oct 2022

Keywords

  • cholestasis
  • cholesterol
  • dyslipidemia
  • hyperviscosity syndrome
  • lipids
  • lipoprotein
  • lipoprotein-X
  • lipoprotein-Z

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