Lipopolysaccharide-mediated injury to cultured human glomerular endothelial cells

Ganesh Raghu; Liliane J. Striker; Gary E. Striker

doi:10.1016/0090-1229(86)90237-0

Lipopolysaccharide-mediated injury to cultured human glomerular endothelial cells

Ganesh Raghu
, Liliane J. Striker
, Gary E. Striker

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Lipopolysaccharide induced a dose-dependent detachment of human glomerular cells in vitro. The detachment occurred 24 hr after exposure to endotoxin. Human umbilical vein endothelial cells were not affected by more prolonged exposure or higher concentrations of lipopolysaccharide in the medium. The lipopolysaccharide effect was independent of complement components or leukocytes.

Original language	English
Pages (from-to)	275-281
Number of pages	7
Journal	Clinical Immunology and Immunopathology
Volume	38
Issue number	3
DOIs	https://doi.org/10.1016/0090-1229(86)90237-0
State	Published - Mar 1986
Externally published	Yes

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@article{413823b10ea442809b949650bc5a822a,

title = "Lipopolysaccharide-mediated injury to cultured human glomerular endothelial cells",

abstract = "Lipopolysaccharide induced a dose-dependent detachment of human glomerular cells in vitro. The detachment occurred 24 hr after exposure to endotoxin. Human umbilical vein endothelial cells were not affected by more prolonged exposure or higher concentrations of lipopolysaccharide in the medium. The lipopolysaccharide effect was independent of complement components or leukocytes.",

author = "Ganesh Raghu and Striker, \{Liliane J.\} and Striker, \{Gary E.\}",

note = "Funding Information: {\textquoteright} This work was supported by Grants GM 29853 and HL 30542 from the National Institutes of Health. Dr. G. Raghu is the recipient of National Research Scholarship Award from the NIH (NL 067455). ? To whom reprint requests should be addressed: NIH, NIADDK, Metabolic Diseases Branch. Building 10. Room 3Nll0, Bethesda, Md. 20205.",

year = "1986",

month = mar,

doi = "10.1016/0090-1229(86)90237-0",

language = "English",

volume = "38",

pages = "275--281",

journal = "Clinical Immunology and Immunopathology",

issn = "0090-1229",

publisher = "Academic Press Inc.",

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TY - JOUR

T1 - Lipopolysaccharide-mediated injury to cultured human glomerular endothelial cells

AU - Raghu, Ganesh

AU - Striker, Liliane J.

AU - Striker, Gary E.

N1 - Funding Information: ’ This work was supported by Grants GM 29853 and HL 30542 from the National Institutes of Health. Dr. G. Raghu is the recipient of National Research Scholarship Award from the NIH (NL 067455). ? To whom reprint requests should be addressed: NIH, NIADDK, Metabolic Diseases Branch. Building 10. Room 3Nll0, Bethesda, Md. 20205.

PY - 1986/3

Y1 - 1986/3

N2 - Lipopolysaccharide induced a dose-dependent detachment of human glomerular cells in vitro. The detachment occurred 24 hr after exposure to endotoxin. Human umbilical vein endothelial cells were not affected by more prolonged exposure or higher concentrations of lipopolysaccharide in the medium. The lipopolysaccharide effect was independent of complement components or leukocytes.

AB - Lipopolysaccharide induced a dose-dependent detachment of human glomerular cells in vitro. The detachment occurred 24 hr after exposure to endotoxin. Human umbilical vein endothelial cells were not affected by more prolonged exposure or higher concentrations of lipopolysaccharide in the medium. The lipopolysaccharide effect was independent of complement components or leukocytes.

UR - https://www.scopus.com/pages/publications/0022640320

U2 - 10.1016/0090-1229(86)90237-0

DO - 10.1016/0090-1229(86)90237-0

M3 - Article

C2 - 3943227

AN - SCOPUS:0022640320

SN - 0090-1229

VL - 38

SP - 275

EP - 281

JO - Clinical Immunology and Immunopathology

JF - Clinical Immunology and Immunopathology

IS - 3

ER -

Lipopolysaccharide-mediated injury to cultured human glomerular endothelial cells

Abstract

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