TY - JOUR
T1 - Leukocyte behavior in atherosclerosis, myocardial infarction, and heart failure
AU - Swirski, Filip K.
AU - Nahrendorf, Matthias
PY - 2013/1/11
Y1 - 2013/1/11
N2 - Cardiovascular diseases claim more lives worldwide than any other. Etiologically, the dominant trajectory involves atherosclerosis, a chronic inflammatory process of lipid-rich lesion growth in the vascular wall that can cause life-threatening myocardial infarction (MI). Those who survive MI can develop congestive heart failure, a chronic condition of inadequate pump activity that is frequently fatal. Leukocytes (white blood cells) are important participants at the various stages of cardiovascular disease progression and complication. This Review will discuss leukocyte function in atherosclerosis, MI, and heart failure.
AB - Cardiovascular diseases claim more lives worldwide than any other. Etiologically, the dominant trajectory involves atherosclerosis, a chronic inflammatory process of lipid-rich lesion growth in the vascular wall that can cause life-threatening myocardial infarction (MI). Those who survive MI can develop congestive heart failure, a chronic condition of inadequate pump activity that is frequently fatal. Leukocytes (white blood cells) are important participants at the various stages of cardiovascular disease progression and complication. This Review will discuss leukocyte function in atherosclerosis, MI, and heart failure.
UR - http://www.scopus.com/inward/record.url?scp=84872166189&partnerID=8YFLogxK
U2 - 10.1126/science.1230719
DO - 10.1126/science.1230719
M3 - Review article
AN - SCOPUS:84872166189
SN - 0036-8075
VL - 339
SP - 161
EP - 166
JO - Science
JF - Science
IS - 6116
ER -