Lesion of a serotonergic modulatory neuron in Aplysia produces a specific defect in feeding behavior

Steven C. Rosen; Irving Kupfermann; Ronald S. Goldstein; Klaudiusz R. Weiss

doi:10.1016/0006-8993(83)90778-3

Lesion of a serotonergic modulatory neuron in Aplysia produces a specific defect in feeding behavior

Steven C. Rosen, Irving Kupfermann, Ronald S. Goldstein, Klaudiusz R. Weiss

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Abstract

The serotonergic metacerebral cells (MCCs) of Aplysia were destroyed by intracellular injection of proteolytic enzyme. MCC-lesioned animals showed alterations of biting responses compared to MCC-sham and B-cell-lesioned control animals, as well as to their own preoperative behavior. The alterations of biting responses included a prolongation of the duration of radula protraction and a lengthening of interbite interval. No changes were observed in non-biting feeding responses and in behaviors unrelated to feeding.

Original language	English
Pages (from-to)	151-155
Number of pages	5
Journal	Brain Research
Volume	260
Issue number	1
DOIs	https://doi.org/10.1016/0006-8993(83)90778-3
State	Published - 31 Jan 1983
Externally published	Yes

Keywords

arousal
feeding
hunger
lesion
mollusc
neuromodulation
serotonin

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10.1016/0006-8993(83)90778-3

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title = "Lesion of a serotonergic modulatory neuron in Aplysia produces a specific defect in feeding behavior",

abstract = "The serotonergic metacerebral cells (MCCs) of Aplysia were destroyed by intracellular injection of proteolytic enzyme. MCC-lesioned animals showed alterations of biting responses compared to MCC-sham and B-cell-lesioned control animals, as well as to their own preoperative behavior. The alterations of biting responses included a prolongation of the duration of radula protraction and a lengthening of interbite interval. No changes were observed in non-biting feeding responses and in behaviors unrelated to feeding.",

keywords = "arousal, feeding, hunger, lesion, mollusc, neuromodulation, serotonin",

author = "Rosen, \{Steven C.\} and Irving Kupfermann and Goldstein, \{Ronald S.\} and Weiss, \{Klaudiusz R.\}",

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T1 - Lesion of a serotonergic modulatory neuron in Aplysia produces a specific defect in feeding behavior

AU - Rosen, Steven C.

AU - Kupfermann, Irving

AU - Goldstein, Ronald S.

AU - Weiss, Klaudiusz R.

PY - 1983/1/31

Y1 - 1983/1/31

N2 - The serotonergic metacerebral cells (MCCs) of Aplysia were destroyed by intracellular injection of proteolytic enzyme. MCC-lesioned animals showed alterations of biting responses compared to MCC-sham and B-cell-lesioned control animals, as well as to their own preoperative behavior. The alterations of biting responses included a prolongation of the duration of radula protraction and a lengthening of interbite interval. No changes were observed in non-biting feeding responses and in behaviors unrelated to feeding.

AB - The serotonergic metacerebral cells (MCCs) of Aplysia were destroyed by intracellular injection of proteolytic enzyme. MCC-lesioned animals showed alterations of biting responses compared to MCC-sham and B-cell-lesioned control animals, as well as to their own preoperative behavior. The alterations of biting responses included a prolongation of the duration of radula protraction and a lengthening of interbite interval. No changes were observed in non-biting feeding responses and in behaviors unrelated to feeding.

KW - arousal

KW - feeding

KW - hunger

KW - lesion

KW - mollusc

KW - neuromodulation

KW - serotonin

UR - https://www.scopus.com/pages/publications/0020694586

U2 - 10.1016/0006-8993(83)90778-3

DO - 10.1016/0006-8993(83)90778-3

M3 - Article

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AN - SCOPUS:0020694586

SN - 0006-8993

VL - 260

SP - 151

EP - 155

JO - Brain Research

JF - Brain Research

IS - 1

ER -

Lesion of a serotonergic modulatory neuron in Aplysia produces a specific defect in feeding behavior

Abstract

Keywords

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