Lesch-Nyhan syndrome: Preventive control by prenatal diagnosis

J. A. Boyle; K. O. Raivio; K. H. Astrin; J. D. Schulman; M. L. Graf; J. E. Seegmiller; C. B. Jacobsen

doi:10.1126/science.169.3946.688

Lesch-Nyhan syndrome: Preventive control by prenatal diagnosis

J. A. Boyle
, K. O. Raivio
, K. H. Astrin
, J. D. Schulman
, M. L. Graf
, J. E. Seegmiller
, C. B. Jacobsen

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

Abstract

The Lesch-Nyhan syndrome was detected in a fetus at a time sufficiently early to allow termination of the pregnancy. The feasibility of a preventive program for control of a severe sex-linked neurological disease through prenatal diagnosis is thus demonstrated.

Original language	English
Pages (from-to)	688-689
Number of pages	2
Journal	Science
Volume	169
Issue number	3946
DOIs	https://doi.org/10.1126/science.169.3946.688
State	Published - 1970
Externally published	Yes

Access to Document

10.1126/science.169.3946.688

Cite this

@article{f9e6297f7b134f3ea461c29f12d4c940,

title = "Lesch-Nyhan syndrome: Preventive control by prenatal diagnosis",

abstract = "The Lesch-Nyhan syndrome was detected in a fetus at a time sufficiently early to allow termination of the pregnancy. The feasibility of a preventive program for control of a severe sex-linked neurological disease through prenatal diagnosis is thus demonstrated.",

author = "Boyle, \{J. A.\} and Raivio, \{K. O.\} and Astrin, \{K. H.\} and Schulman, \{J. D.\} and Graf, \{M. L.\} and Seegmiller, \{J. E.\} and Jacobsen, \{C. B.\}",

year = "1970",

doi = "10.1126/science.169.3946.688",

language = "English",

volume = "169",

pages = "688--689",

journal = "Science",

issn = "0036-8075",

publisher = "American Association for the Advancement of Science",

number = "3946",

}

TY - JOUR

T1 - Lesch-Nyhan syndrome

T2 - Preventive control by prenatal diagnosis

AU - Boyle, J. A.

AU - Raivio, K. O.

AU - Astrin, K. H.

AU - Schulman, J. D.

AU - Graf, M. L.

AU - Seegmiller, J. E.

AU - Jacobsen, C. B.

PY - 1970

Y1 - 1970

N2 - The Lesch-Nyhan syndrome was detected in a fetus at a time sufficiently early to allow termination of the pregnancy. The feasibility of a preventive program for control of a severe sex-linked neurological disease through prenatal diagnosis is thus demonstrated.

AB - The Lesch-Nyhan syndrome was detected in a fetus at a time sufficiently early to allow termination of the pregnancy. The feasibility of a preventive program for control of a severe sex-linked neurological disease through prenatal diagnosis is thus demonstrated.

UR - https://www.scopus.com/pages/publications/0014945271

U2 - 10.1126/science.169.3946.688

DO - 10.1126/science.169.3946.688

M3 - Article

C2 - 5464303

AN - SCOPUS:0014945271

SN - 0036-8075

VL - 169

SP - 688

EP - 689

JO - Science

JF - Science

IS - 3946

ER -

Lesch-Nyhan syndrome: Preventive control by prenatal diagnosis

Abstract

Access to Document

Fingerprint

Cite this