Lesch-Nyhan syndrome: Preventive control by prenatal diagnosis

J. A. Boyle; K. O. Raivio; K. H. Astrin; J. D. Schulman; M. L. Graf; J. E. Seegmiller; C. B. Jacobsen

doi:10.1126/science.169.3946.688

Lesch-Nyhan syndrome: Preventive control by prenatal diagnosis

J. A. Boyle, K. O. Raivio, K. H. Astrin, J. D. Schulman, M. L. Graf, J. E. Seegmiller, C. B. Jacobsen

Research output: Contribution to journal › Article › peer-review

41 Scopus citations

Abstract

The Lesch-Nyhan syndrome was detected in a fetus at a time sufficiently early to allow termination of the pregnancy. The feasibility of a preventive program for control of a severe sex-linked neurological disease through prenatal diagnosis is thus demonstrated.

Original language	English
Pages (from-to)	688-689
Number of pages	2
Journal	Science
Volume	169
Issue number	3946
DOIs	https://doi.org/10.1126/science.169.3946.688
State	Published - 1970
Externally published	Yes

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title = "Lesch-Nyhan syndrome: Preventive control by prenatal diagnosis",

abstract = "The Lesch-Nyhan syndrome was detected in a fetus at a time sufficiently early to allow termination of the pregnancy. The feasibility of a preventive program for control of a severe sex-linked neurological disease through prenatal diagnosis is thus demonstrated.",

author = "Boyle, {J. A.} and Raivio, {K. O.} and Astrin, {K. H.} and Schulman, {J. D.} and Graf, {M. L.} and Seegmiller, {J. E.} and Jacobsen, {C. B.}",

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T2 - Preventive control by prenatal diagnosis

AU - Boyle, J. A.

AU - Raivio, K. O.

AU - Astrin, K. H.

AU - Schulman, J. D.

AU - Graf, M. L.

AU - Seegmiller, J. E.

AU - Jacobsen, C. B.

PY - 1970

Y1 - 1970

N2 - The Lesch-Nyhan syndrome was detected in a fetus at a time sufficiently early to allow termination of the pregnancy. The feasibility of a preventive program for control of a severe sex-linked neurological disease through prenatal diagnosis is thus demonstrated.

AB - The Lesch-Nyhan syndrome was detected in a fetus at a time sufficiently early to allow termination of the pregnancy. The feasibility of a preventive program for control of a severe sex-linked neurological disease through prenatal diagnosis is thus demonstrated.

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M3 - Article

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SN - 0036-8075

VL - 169

SP - 688

EP - 689

JO - Science

JF - Science

IS - 3946

ER -

Lesch-Nyhan syndrome: Preventive control by prenatal diagnosis

Abstract

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