Leadless Cardiac Pacemakers Back to the Future

Marc A. Miller, Petr Neuzil, Srinivas R. Dukkipati, Vivek Y. Reddy

Research output: Contribution to journalReview articlepeer-review

89 Scopus citations


Despite significant advances in battery longevity, lead performance, and programming features since the first implanted permanent pacemaker was developed, the basic design of cardiac pacemakers has remained relatively unchanged over the past 50 years. Because of inherent limitations in their design, conventional (transvenous) pacemakers are prone to multiple potential short- and long-term complications. Accordingly, there has been intense interest in a system able to provide the symptomatic and potentially lifesaving therapies of cardiac pacemakers while mitigating many of the risks associated with their weakest link - the transvenous lead. Leadless cardiac pacing represents the future of cardiac pacing systems, similar to the transition that occurred from the use of epicardial pacing systems to the familiar transvenous systems of today. This review summarizes the current evidence and potential benefits of leadless pacing systems, which are either commercially available (in Europe) or under clinical investigation.

Original languageEnglish
Pages (from-to)1179-1189
Number of pages11
JournalJournal of the American College of Cardiology
Issue number10
StatePublished - 8 Sep 2015


  • brachycardia
  • cardiac resynchronization therapy
  • electrophysiology


Dive into the research topics of 'Leadless Cardiac Pacemakers Back to the Future'. Together they form a unique fingerprint.

Cite this