Lactic acidosis after treatment with linezolid

M. Wiener; Y. Guo; G. Patel; B. C. Fries

doi:10.1007/s15010-007-6302-x

Lactic acidosis after treatment with linezolid

M. Wiener, Y. Guo, G. Patel, B. C. Fries

Research output: Contribution to journal › Review article › peer-review

36 Scopus citations

Abstract

Linezolid is currently indicated to treat vancomycin-resistant Enterococcus faecium infections, nosocomial pneumonia caused by Staphylococcus aureus or Streptococcus pneumoniae, complicated and uncomplicated skin and skin structure infections, and community-acquired pneumonia. We report a case of linezolid-induced lactic acidosis during treatment of vancomycin-resistant enterococcal bacteremia after mitral valve replacement and permanent pacemaker implantation. We also review the current literature describing other cases of linezolid-associated hyperlactatemia.

Original language	English
Pages (from-to)	278-281
Number of pages	4
Journal	Infection
Volume	35
Issue number	4
DOIs	https://doi.org/10.1007/s15010-007-6302-x
State	Published - Aug 2007

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title = "Lactic acidosis after treatment with linezolid",

abstract = "Linezolid is currently indicated to treat vancomycin-resistant Enterococcus faecium infections, nosocomial pneumonia caused by Staphylococcus aureus or Streptococcus pneumoniae, complicated and uncomplicated skin and skin structure infections, and community-acquired pneumonia. We report a case of linezolid-induced lactic acidosis during treatment of vancomycin-resistant enterococcal bacteremia after mitral valve replacement and permanent pacemaker implantation. We also review the current literature describing other cases of linezolid-associated hyperlactatemia.",

author = "M. Wiener and Y. Guo and G. Patel and Fries, {B. C.}",

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AU - Wiener, M.

AU - Guo, Y.

AU - Patel, G.

AU - Fries, B. C.

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N2 - Linezolid is currently indicated to treat vancomycin-resistant Enterococcus faecium infections, nosocomial pneumonia caused by Staphylococcus aureus or Streptococcus pneumoniae, complicated and uncomplicated skin and skin structure infections, and community-acquired pneumonia. We report a case of linezolid-induced lactic acidosis during treatment of vancomycin-resistant enterococcal bacteremia after mitral valve replacement and permanent pacemaker implantation. We also review the current literature describing other cases of linezolid-associated hyperlactatemia.

AB - Linezolid is currently indicated to treat vancomycin-resistant Enterococcus faecium infections, nosocomial pneumonia caused by Staphylococcus aureus or Streptococcus pneumoniae, complicated and uncomplicated skin and skin structure infections, and community-acquired pneumonia. We report a case of linezolid-induced lactic acidosis during treatment of vancomycin-resistant enterococcal bacteremia after mitral valve replacement and permanent pacemaker implantation. We also review the current literature describing other cases of linezolid-associated hyperlactatemia.

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SP - 278

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JO - Infection

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ER -

Lactic acidosis after treatment with linezolid

Abstract

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