Label-free mass quantitation of individual cathepsin K enzymes using interferrometric scattering microscopy

Luke Melo, Pierre Marie Andrault, Matthew Kowal, Dieter Brömme, Edward Grant

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Interferrometric scattering microscopy is used to mass quantify individual Cathepsin K enzymes in solution. Treatments for osteoporosis are assessed by monitoring the oligomerization of Cathepsin K.

Original languageEnglish
Title of host publicationComputational Optical Sensing and Imaging, COSI 2020
PublisherThe Optical Society
ISBN (Electronic)9781557528209
StatePublished - 2020
Externally publishedYes
EventComputational Optical Sensing and Imaging, COSI 2020 - Part of Imaging and Applied Optics Congress 2020 - Virtual, Online, United States
Duration: 22 Jun 202026 Jun 2020

Publication series

NameOptics InfoBase Conference Papers

Conference

ConferenceComputational Optical Sensing and Imaging, COSI 2020 - Part of Imaging and Applied Optics Congress 2020
Country/TerritoryUnited States
CityVirtual, Online
Period22/06/2026/06/20

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