La gastroentérite à éosinophiles

Translated title of the contribution: Eosinophilic gastroenteritis

G. Pineton de Chambrun, P. Desreumaux, J. F. Colombel, A. Cortot

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Eosinophilic gastroenteritis is a rare gastrointestinal disorder of unknown etiology characterized by an infiltration of the intestines by polynuclear eosinophils. The role of allergy in eosinophilic gastroenteritis remains controversial, since an allergic background is present in only half of the patients who present with a personal or familial history of allergy. It is responsible for various digestive symptoms which depend on the depth of eosinophilic infiltration in the digestive wall and the bowel segments involved. Its diagnosis is difficult, requiring elimination of other causes having secondary intestinal eosinophilic infiltration, such as intestinal parasitosis, essential hypereosinophilic syndrome, certain drugs, and neoplasia. Treatment is based essentially on oral corticosteroids used over a short period. Its evolution is benign, with no relapse after the first attack in the majority of cases. However, a certain number of patients have a more complicated course marked either by unpredictable corticosteroids-sensitive recurrences or by a chronic corticoid-dependent course requiring maintenance therapy with antihistaminic or immunosuppressive drugs.

Translated title of the contributionEosinophilic gastroenteritis
Original languageFrench
Pages (from-to)248-253
Number of pages6
JournalRevue Francaise d'Allergologie
Volume50
Issue number3
DOIs
StatePublished - Apr 2010
Externally publishedYes

Keywords

  • Diagnosis
  • Eosinophilic gastroenteritis
  • Intestinal mucosa
  • Natural history
  • Therapy

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