L-5-Hydroxytryptophan in the treatment of anxiety disorders

RenéS S. Kahn, Herman G.M. Westenberg

Research output: Contribution to journalArticlepeer-review

68 Scopus citations


Ten outpatients suffering from anxiety states (Anxiety Disorders: DSM-III) were treated with L-5-hydroxytryptophan and carbidopa. A significant reduction in anxiety was observed on three different anxiety scales. It is suggested that 5-HT systems may be involved in the mediation of anxiety.

Original languageEnglish
Pages (from-to)197-200
Number of pages4
JournalJournal of Affective Disorders
Issue number2
StatePublished - 1985
Externally publishedYes


  • 5-Hydroxytryptophan
  • Anxiety disorders
  • Serotonin


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