Abstract
Juvenile dermatomyositis (JDM) is a rare disease, and Sjögren's syndrome (SS) is unusual in adolescents. We report the first case of biopsy-proven JDM and SS with pulmonary involvement. A 15-year-old adolescent boy presented with recurrent parotid gland hypertrophy, severe muscle weakness, pronounced skin rash and widespread lymphadenopathy. JDM was diagnosed by clinical examination, elevated muscle enzymes, electromyography and muscle biopsy; SS was diagnosed by xerostomia, anti-Ro (SS-A) positivity and histopathological analysis of salivary gland tissue. This case illustrates a systematic approach which we feel is especially important in the younger patient with a more plastic immune system.
Original language | English |
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Pages (from-to) | 3-5 |
Number of pages | 3 |
Journal | Clinical Rheumatology |
Volume | 27 |
Issue number | SUPPL. 1 |
DOIs | |
State | Published - Jun 2008 |
Externally published | Yes |
Keywords
- Interstitial lung disease
- Juvenile dermatomyositis
- Myocarditis
- Myositis
- Sjögren's syndrome