Jorge Lobo's disease: A case of keloidal blastomycosis (lobomycosis) in a nonendemic area

Rezina Arju, Sherly Abraham, Jiten P. Kothadia, Monica Kaminski, Shah Giashuddin

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations

Abstract

Lobomycosis or lacaziosis is a chronic subcutaneous fungal infection, caused by the fungus Lacazia loboi, which is phylogenetically related to Coccidioides, Blastomyces, Histoplasma, and Paracoccidioides. The disease was first recognized in 1931 by Jorge Lobo, who found the disease to be a keloidal blastomycosis and named it Jorge Lobo's disease. This case was perplexing initially as this fungal infection is very uncommon in the USA. However, with the ever-increasing frequency of international travel, many more cases of lobomycosis have been diagnosed in areas of nonendemicity, such as the USA, Europe, and South Africa. The clinical histories of such imported fungal infections often illustrate their long latency periods. In lobomycosis, the onset of the disease is usually insidious and often difficult to document. We describe a case of a New York resident who presented with multiple skin nodules over both his arms and forearms, and was subsequently diagnosed with Jorge Lobo's disease. The case, diagnosis, histopathologic findings, complication, and management of this rare clinical disease are discussed.

Original languageEnglish
Pages (from-to)91-96
Number of pages6
JournalTherapeutic Advances in Infectious Disease
Volume2
Issue number4
DOIs
StatePublished - Jun 2014
Externally publishedYes

Keywords

  • Jorge Lobo's disease
  • fungal infections
  • keloidal blastomycosis
  • mycoses

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