JCL roundtable: Managing lipid disorders in patients with HIV

W. Virgil Brown, Judith A. Aberg, Karen E. Aspry, Chris T. Longenecker, Merle Myerson

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

The HIV-AIDS epidemic has provided one of the more challenging problems in treatment of infectious diseases. As antiretroviral drugs made a very marked improvement in controlling the immunodeficiency state and patients gained in their longevity, the concern with lipid abnormalities came to the fore. The initial drugs produced a form of metabolic syndrome accompanied by very elevated plasma triglyceride concentrations. Furthermore, the drugs used to control the virus were often metabolized in a manner that interfered with lipid lowering drug therapy. The antiviral agents have improved in many respects and the experience in managing the lipid disorders has added greatly to our ability to control these problems as well. This roundtable discussion has been conducted with 4 physicians who have been involved in management of large cohorts of patients with HIV infection and who have had a special interest in reduction of vascular disease risk.

Original languageEnglish
Pages (from-to)4-11
Number of pages8
JournalJournal of Clinical Lipidology
Volume11
Issue number1
DOIs
StatePublished - 1 Jan 2017

Keywords

  • AIDS
  • Antiretroviral drugs
  • HIV
  • Immunodeficiency
  • Infectious diseases
  • Lipid disorders

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