TY - JOUR
T1 - Isolation of troponin like complex from bovine brain cortex
AU - Mahendran, C.
AU - Berl, S.
PY - 1977
Y1 - 1977
N2 - A troponin-like complex has been isolated from bovine brain cortex. This troponin-like complex, with brain tropomyosin, confers Ca2+ sensitivity to the actin-activated myosin adenosinetriphosphatase (ATP phosphohydrolase, EC 3.6.1.3). That is, the Mg2+-stimulated ATPase activity generated by the interaction of purified muscle actin with muscle myosin is inhibited in the absence of Ca2+ but not in the presence of Ca2+ as a result of the addition of both brain tropomyosin and troponin-like complex. The troponin-like complex contains 3 components, one of which is similar in molecular weight to the troponin T of skeletal actomyosin.
AB - A troponin-like complex has been isolated from bovine brain cortex. This troponin-like complex, with brain tropomyosin, confers Ca2+ sensitivity to the actin-activated myosin adenosinetriphosphatase (ATP phosphohydrolase, EC 3.6.1.3). That is, the Mg2+-stimulated ATPase activity generated by the interaction of purified muscle actin with muscle myosin is inhibited in the absence of Ca2+ but not in the presence of Ca2+ as a result of the addition of both brain tropomyosin and troponin-like complex. The troponin-like complex contains 3 components, one of which is similar in molecular weight to the troponin T of skeletal actomyosin.
UR - https://www.scopus.com/pages/publications/0017407515
U2 - 10.1073/pnas.74.6.2273
DO - 10.1073/pnas.74.6.2273
M3 - Article
C2 - 142251
AN - SCOPUS:0017407515
SN - 0027-8424
VL - 74
SP - 2273
EP - 2277
JO - Proceedings of the National Academy of Sciences of the United States of America
JF - Proceedings of the National Academy of Sciences of the United States of America
IS - 6
ER -