TY - JOUR
T1 - Isolation and characterization of a novel retrovirus from sheep affected by pulmonary carcinoma
AU - Irving, Steven G.
AU - Perk, Kalman
AU - Hod, Israel
AU - Gazit, Arnona
AU - Yaniv, Abraham
AU - Zimber, Amazia
AU - Tal, Michael
N1 - Funding Information:
This investigation was supported the United States-Israel Agricultural Development Fund (BARD).
PY - 1984/4/15
Y1 - 1984/4/15
N2 - Sheep pulmonary carcinoma (SPC) has been shown to be associated in nature with a retrovirus, by electron microscopic, biochemical, and epidemiological criteria and by experimental transmission. In this study, a retrovirus has been isolated from SPC tumors which were experimentally induced by inoculation with a cell-free, reverse transcriptase containing fraction from a spontaneous field case of SPC, and propagated in culture. This novel virus was shown to be unrelated to murine, avian, and bovine leukemia viruses, to be exogenous to the ovine species, and to have only limited genetic relatedness to the lentiviridae (maedi-visna and caprine arthritis encephalitis virus).
AB - Sheep pulmonary carcinoma (SPC) has been shown to be associated in nature with a retrovirus, by electron microscopic, biochemical, and epidemiological criteria and by experimental transmission. In this study, a retrovirus has been isolated from SPC tumors which were experimentally induced by inoculation with a cell-free, reverse transcriptase containing fraction from a spontaneous field case of SPC, and propagated in culture. This novel virus was shown to be unrelated to murine, avian, and bovine leukemia viruses, to be exogenous to the ovine species, and to have only limited genetic relatedness to the lentiviridae (maedi-visna and caprine arthritis encephalitis virus).
UR - http://www.scopus.com/inward/record.url?scp=0021354156&partnerID=8YFLogxK
U2 - 10.1016/0042-6822(84)90291-5
DO - 10.1016/0042-6822(84)90291-5
M3 - Article
C2 - 6324472
AN - SCOPUS:0021354156
SN - 0042-6822
VL - 134
SP - 244
EP - 248
JO - Virology
JF - Virology
IS - 1
ER -