TY - JOUR
T1 - Is RNA interference a physiologically relevant innate antiviral immune response in mammals?
AU - Cullen, Bryan R.
AU - Cherry, Sara
AU - Tenoever, Benjamin R.
PY - 2013/10/16
Y1 - 2013/10/16
N2 - While RNA interference (RNAi) functions as an antiviral response in plants, nematodes, and arthropods, a similar antiviral role in mammals has remained controversial. Three recent papers provide evidence that either favors or challenges this hypothesis. Here, we discuss these new findings in the context of previous research.
AB - While RNA interference (RNAi) functions as an antiviral response in plants, nematodes, and arthropods, a similar antiviral role in mammals has remained controversial. Three recent papers provide evidence that either favors or challenges this hypothesis. Here, we discuss these new findings in the context of previous research.
UR - http://www.scopus.com/inward/record.url?scp=84886066428&partnerID=8YFLogxK
U2 - 10.1016/j.chom.2013.09.011
DO - 10.1016/j.chom.2013.09.011
M3 - Review article
C2 - 24139396
AN - SCOPUS:84886066428
SN - 1931-3128
VL - 14
SP - 374
EP - 378
JO - Cell Host and Microbe
JF - Cell Host and Microbe
IS - 4
ER -