Is RNA interference a physiologically relevant innate antiviral immune response in mammals?

Bryan R. Cullen, Sara Cherry, Benjamin R. Tenoever

Research output: Contribution to journalReview articlepeer-review

104 Scopus citations

Abstract

While RNA interference (RNAi) functions as an antiviral response in plants, nematodes, and arthropods, a similar antiviral role in mammals has remained controversial. Three recent papers provide evidence that either favors or challenges this hypothesis. Here, we discuss these new findings in the context of previous research.

Original languageEnglish
Pages (from-to)374-378
Number of pages5
JournalCell Host and Microbe
Volume14
Issue number4
DOIs
StatePublished - 16 Oct 2013

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