Is growth hormone resistance/IGF-1 reduction good for you?

Research output: Contribution to journalShort surveypeer-review

22 Scopus citations

Abstract

GH, IGF-1, and insulin are emerging as important and independent mediators of tumor development and aging. Two recent studies report that humans with GH-receptor deficiency are protected from developing cancer through alterations in GH, IGF-1, and insulin signaling, decreasing the susceptibility of cells to DNA damage and abnormal proliferation.

Original languageEnglish
Pages (from-to)355-356
Number of pages2
JournalCell Metabolism
Volume13
Issue number4
DOIs
StatePublished - 6 Apr 2011
Externally publishedYes

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