Irritable bowel syndrome

Irritable bowel syndrome (IBS) is considered to be a biopsychosocial illness, with colonic dysfunction and alterations in the brain-gut axis, often in the context of psychosocial issues. While quality of life is as impaired as in patients with inflammatory bowel disease, diagnostic tests are normal and usually unnecessary. Diagnosis is made on the basis of symptoms such as bowel dysfunction and abdominal pain. IBS may be related, in part, to diet, to colonic dysmotility, to visceral hypersensitivity, and to psychological issues. Treatment includes pharmaceuticals, alternative remedies, various forms of psychotherapy, and a supportive doctor-patient relationship.