Iron Overload

Yelena Z. Ginzburg; Francesca Vinchi

doi:10.1016/B978-0-323-96014-4.00067-7

Iron Overload

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Iron overload is a progressive accumulation of iron in vital organs (e.g., liver, heart, pancreas, and endocrine organs) caused by an excess of systemic iron. When untreated, iron overload increases the risk of liver cirrhosis, heart failure, diabetes mellitus, osteoporosis, hypogonadism, and neurodegenerative symptoms. These potentially fatal complications are preventable by iron depletion therapies.

Original language	English
Title of host publication	Transfusion Medicine and Hemostasis
Subtitle of host publication	Clinical and Laboratory Aspects
Publisher	Elsevier
Pages	367-369
Number of pages	3
ISBN (Electronic)	9780323960144
ISBN (Print)	9780323960151
DOIs	https://doi.org/10.1016/B978-0-323-96014-4.00067-7
State	Published - 1 Jan 2024

Keywords

Chronic transfusion
Hemochromatosis
Iron chelation
Iron overload

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10.1016/B978-0-323-96014-4.00067-7

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AB - Iron overload is a progressive accumulation of iron in vital organs (e.g., liver, heart, pancreas, and endocrine organs) caused by an excess of systemic iron. When untreated, iron overload increases the risk of liver cirrhosis, heart failure, diabetes mellitus, osteoporosis, hypogonadism, and neurodegenerative symptoms. These potentially fatal complications are preventable by iron depletion therapies.

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KW - Iron chelation

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BT - Transfusion Medicine and Hemostasis

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ER -

Iron Overload

Abstract

Keywords

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