Several invasive procedures are now commonly performed in multifetal pregnancies. Techniques for prenatal diagnosis performed in multifetal pregnancies, such as amniocentesis and CVS, present specific technical challenges when compared with their performance in singletons and are best performed by experienced operators to increase the success of the procedure, reduce contamination, and minimize postprocedure complications. Procedures developed to cope with the sequelae specific to multifetal pregnancies, such as multifetal pregnancy reduction and selective termination, are also commonly performed with generally good outcomes. The moral and psychologic issues associated with these procedures are extensive and complex for the patient and the physician, but it is clear that pregnancy outcomes of high-order multiples (triplets and up) are improved by multifetal pregnancy reduction. It is hope that with better regulation of assisted reproductive techniques, the need for these specialized procedures will become obsolete.

Original languageEnglish
Pages (from-to)355-371
Number of pages17
JournalClinics in Perinatology
Issue number2
StatePublished - Jun 2005


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