Invasive epithelial ovarian cancer

Brittney S. Zimmerman, Jeannette Guziel, Amy Tiersten

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


This chapter presents the definition, classification, incidence/prevalence, economic impact, etiology and risk factors, and pathology/pathogenesis of invasive epithelial ovarian cancer. Ovarian cancer is the leading cause of death from gynecologic cancer in the USA and the fifth most common cause of cancer mortality in females. The incidence of ovarian cancer increases with age. The average age at diagnosis of ovarian cancer in the USA is 63 years. The chapter also includes the potential pitfalls/common errors made regarding diagnosis of disease, diagnostic and treatment algorithms, prevention/management of complications, important scientific studies, evidence-based clinical data, and essential social guidelines for invasive epithelial ovarian cancer. The majority of ovarian cancers are diagnosed at an advanced stage: confined to primary site; regional lymph nodes; distant metastases; and unstaged. Ovarian cancer is a very chemo-responsive disease and advances in therapies have resulted in improved survival.

Original languageEnglish
Title of host publicationOncology
Number of pages15
ISBN (Electronic)9781119189596
ISBN (Print)9781119189558
StatePublished - 30 Aug 2019


  • Chemotherapy
  • Diagnostic algorithms
  • Evidence-based clinical data
  • Invasive epithelial ovarian cancer
  • Treatment algorithms


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