Abstract

This Teaching Resource provides lecture notes, slides, and a problem set for a series of lectures introducing the mathematical concepts behind gene-set enrichment analysis (GSEA ) and were part of a course entitled "Systems Biology: Biomedical Modeling." GSEA is a statistical functional enrichment analysis commonly applied to identify enrichment of biological functional categories in sets of ranked differentially expressed genes from genome-wide mRNA expression data sets.

Original languageEnglish
Article numbertr4
JournalScience Signaling
Volume4
Issue number190
DOIs
StatePublished - 13 Sep 2011

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