Intravitreal injection of tissue plasminogen activator as treatment for an occluded pars plana glaucoma tube

Irena Tsui, Suzanna Airiani, Angie Wen, Tarek El-Sawy, Howard F. Fine, Peter J.G. Maris

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Implanting glaucoma tubes through the pars plana in the setting of a corneal transplant is becoming more common, and there are unique problems associated with such a procedure. A 42-year-old man with multiple previous eye surgeries presented with a nonfunctioning pars plana glaucoma tube. There was no view to the tube tip, but it was presumed to be clogged with fibrin. Intravitreal tissue plasminogen activator (tPA) was injected through the pars plana which resulted in intraocular pressure control without further surgery. This new application of intravitreal tPA has not been reported previously. Future research should investigate the optimal effective and safe dose of intravitreal tPA injection to relieve such occlusions.

Original languageEnglish
Pages (from-to)91-93
Number of pages3
JournalClinical Ophthalmology
Volume3
Issue number1
StatePublished - 2009
Externally publishedYes

Keywords

  • Ahmed glaucoma valve
  • Tissue plasminogen activator (tPA)

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