Intraoperative haemodynamics and postoperative intensive care unit admission in older patients with cancer

Anoushka M. Afonso, Dahniel Sastow, Joshua B. Cadwell, Robert J. Downey, Gregory W. Fischer, Armin Shahrokni

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: Research on the impact of various intraoperative haemodynamic variables on the incidence of postoperative ICU admission among older patients with cancer is limited. In this study, the relationship between intraoperative haemodynamic status and postoperative intensive care unit admission among older patients with cancer is explored. Methods: Patients aged ≥75 who underwent elective oncologic surgery lasting ≥120min were analysed. Chi-squared and t-tests were used to assess the associations between intraoperative variables with postoperative intensive care unit admission. Multivariable regressions were used to analyse potential predict risk factors for postoperative intensive care unit admission. Results: Out of 994 patients, 48 (4.8%) were admitted to the intensive care unit within 30 days following surgery. Intensive care unit admission was associated with the presence of ≥4 comorbid conditions, intraoperative blood loss ≥100mL, and intraoperative tachycardia and hypertensive urgency. On multivariable analysis, operation time ≥240min (Odds Ratio [OR] = 2.29, p = 0.01), and each minute spent with intraoperative hypertensive urgency (OR = 1.06, p = 0.01) or tachycardia (OR = 1.01, p = 0.002) were associated with postoperative intensive care unit admission. Conclusion: Intraoperative hypertensive urgency and tachycardia were associated with postoperative intensive care unit admission in older patients undergoing cancer surgery.

Original languageEnglish
Pages (from-to)301-309
Number of pages9
JournalJournal of perioperative practice
Volume32
Issue number11
DOIs
StatePublished - Nov 2022
Externally publishedYes

Keywords

  • Geriatrics
  • Haemodynamics
  • Hypertensive urgency
  • Intensive care unit admission
  • Perioperative outcome
  • Tachycardia

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