Intraductal polypoid lipid-rich neuroendocrine tumor of the pancreas with entrapped ductules: Case report and review of the literature

Jaclyn Frances Hechtman, Bernardo Franssen, Daniel M. Labow, Ronald E. Gordon, Christopher J. Dimaio, Eric J. Wilck, Gonzalo Carrasco-Avino, Hongfa Zhu

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Pancreatic neuroendocrine tumors of the main pancreatic duct are rare and usually small due to symptoms of pancreatic duct obstruction. We present a case of a large (3 cm), well-differentiated (G1) lipid-rich polypoid neuroendocrine tumor of the pancreas completely occluding the main pancreatic duct with non-neoplastic-entrapped ductules and CK19 positivity. Clinical, radiological, gross, microscopic, immunohistochemical, and ultrastructural findings are discussed. The literature pertaining to the unique features of this case is reviewed including clinical and pathologic pitfalls and the possible etiologic and prognostic significance of these findings.

Original languageEnglish
Pages (from-to)30-35
Number of pages6
JournalEndocrine Pathology
Volume24
Issue number1
DOIs
StatePublished - Mar 2013

Keywords

  • CK19
  • Carcinoid
  • Clear cell
  • Ductulo-insular
  • Entrapped glands
  • Intraductal
  • Lipid rich
  • Neuroendocrine tumor
  • Pancreas
  • Pancreatic
  • Polypoid

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