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Interventions and Outcomes in Patients with Infectious Pseudomonas scleritis: A 10-Year Perspective

  • Sumayya Ahmad
  • , Michelle Lopez
  • , Marwan Attala
  • , Anat Galor
  • , Natalie A. Stanciu
  • , Darlene Miller
  • , Leejee Suh
  • , Thomas Albini
  • , Victor L. Perez
  • , Carol L. Karp
  • , Janet L. Davis
  • , Eduardo Alfonso
  • , Richard K. Forster
  • , Guillermo Amescua

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

Purpose: To identify interventional factors associated with improved visual results and faster time to resolution for patients with Pseudomonas scleritis. Methods: Retrospective study analyzing inciting factors, therapeutic modalities, and outcomes of patients with Pseudomonas scleritis. Results: A total of 24 patients were analyzed; 22 were treated as outpatients. All had resolution of infection and 58% (n = 14) maintained ≥20/200 vision. Medical therapy included topical and oral antibiotics; seven received additional subconjunctival injections; two were admitted for IV antibiotics. Patients presenting with ≥20/200 vision were more likely to maintain this level of vision (n = 8, 80%) compared to those presenting with severe vision loss (n = 5, 36%) (p = 0.04). A similar proportion of patients who received (n = 8, 61%) and did not receive (n = 5, 39%) oral steroids achieved 20/200 vision or better once infection resolved, p = 1.0. Conclusions: Pseudomonas scleritis can be successfully managed in the outpatient setting. Oral steroids do not appear harmful in the treatment of this disease.

Original languageEnglish
Pages (from-to)499-506
Number of pages8
JournalOcular Immunology and Inflammation
Volume27
Issue number3
DOIs
StatePublished - 3 Apr 2019

Keywords

  • Infectious scleritis
  • Pseudomonas
  • review
  • steroids

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