Interrupted aortic arch: Diagnosis with gadolinium-enhanced 3D MRA

Kevin J. Roche, Glenn Krinsky, Vivian S. Lee, Neil Rofsky, Nancy B. Genieser

Research output: Contribution to journalArticlepeer-review

42 Scopus citations


Purpose: Our goal was to describe the use of gadolinium-enhanced 3D MR angiography (MRA) in the diagnosis of interrupted aortic arch (IAA). Method: A review of our MR data base from a 1 year period yielded three patients (1 day, 8 days, and 16 years old) with IAA. All were referred for evaluation of aortic arch abnormalities, only one of whom had suspected IAA. Patients were imaged at 1.5 T with a 3D spoiled gradient echo pulse sequence (TR/TE 3.8- 8/1.3-2.7 ms) following the administration of intravenous gadolinium chelates. Surgical correlation was available in all cases. Results: In the patient with clinically suspected IAA, a previously unsuspected aberrant right subclavian artery was identified that was not seen on preoperative echocardiography. In another patient with a history of previous mediastinal surgery, IAA was diagnosed without concomitant cardiac anomalies, suggesting surgical ligation. In the remaining patient, IAA was detected as well as a patent truncus arteriosus. Conclusion: Gadolinium-enhanced 3D MRA may provide for a rapid diagnosis of IAA that may not be possible with other noninvasive modalities. The rapid acquisition time enables unstable pediatric patients to spend minimal time in the MR suite.

Original languageEnglish
Pages (from-to)197-202
Number of pages6
JournalJournal of Computer Assisted Tomography
Issue number2
StatePublished - 1999
Externally publishedYes


  • Anomalies, congenital
  • Aorta, arch
  • Magnetic resonance angiography (MRA)
  • Mediastinum


Dive into the research topics of 'Interrupted aortic arch: Diagnosis with gadolinium-enhanced 3D MRA'. Together they form a unique fingerprint.

Cite this