Interpretation of Rheumatological Tests

Shane Murray, Yousaf Ali

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Joint pain is one of the most common presentations to primary care, and the differentiation between inflammatory and mechanical causes can be challenging. Since autoimmune diseases make up a significant proportion of these patients, serologic testing is important in both diagnosis and clinical decision-making. Unfortunately, due to the presence of autoantibodies in a healthy population, these tests are often perceived as confusing. This chapter will focus on the diagnostic interpretation of normal and abnormal rheumatologic values.

Original languageEnglish
Title of host publicationRheumatology for Primary Care Providers
Subtitle of host publicationA Clinical Casebook
PublisherSpringer International Publishing
Number of pages18
ISBN (Electronic)9783030806996
ISBN (Print)9783030806989
StatePublished - 1 Jan 2021


  • Anti-Smith antibodies
  • Anti-double-stranded DNA antibodies
  • Anticyclic citrullinated peptide antibodies
  • Antineutrophil cytoplasmic antibody
  • Antinuclear antibody
  • C-reactive protein
  • Erythrocyte sedimentation rate
  • Human leukocyte B27 antigen
  • Rheumatoid factor


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