International Society of Nephrology's 0by25 initiative for acute kidney injury (zero preventable deaths by 2025): A human rights case for nephrology

Ravindra L. Mehta; Jorge Cerdá; Emmanuel A. Burdmann; Marcello Tonelli; Guillermo García-García; Vivekanand Jha; Paweena Susantitaphong; Michael Rocco; Raymond Vanholder; Mehmet Sukru Sever; Dinna Cruz; Bertrand Jaber; Norbert H. Lameire; Raúl Lombardi; Andrew Lewington; John Feehally; Fredric Finkelstein; Nathan Levin; Neesh Pannu; Bernadette Thomas; Eliah Aronoff-Spencer; Giuseppe Remuzzi

doi:10.1016/S0140-6736(15)60126-X

International Society of Nephrology's 0by25 initiative for acute kidney injury (zero preventable deaths by 2025): A human rights case for nephrology

Ravindra L. Mehta
, Jorge Cerdá
, Emmanuel A. Burdmann
, Marcello Tonelli
, Guillermo García-García
, Vivekanand Jha
, Paweena Susantitaphong
, Michael Rocco
, Raymond Vanholder
, Mehmet Sukru Sever
, Dinna Cruz
, Bertrand Jaber
, Norbert H. Lameire
, Raúl Lombardi
, Andrew Lewington
, John Feehally
, Fredric Finkelstein
, Nathan Levin
, Neesh Pannu
, Bernadette Thomas

Eliah Aronoff-Spencer, Giuseppe Remuzzi

Research output: Contribution to journal › Review article › peer-review

953 Scopus citations

Original language	English
Pages (from-to)	2616-2643
Number of pages	28
Journal	The Lancet
Volume	385
Issue number	9987
DOIs	https://doi.org/10.1016/S0140-6736(15)60126-X
State	Published - 27 Jun 2015
Externally published	Yes

Access to Document

10.1016/S0140-6736(15)60126-X

Cite this

Mehta, R. L., Cerdá, J., Burdmann, E. A., Tonelli, M., García-García, G., Jha, V., Susantitaphong, P., Rocco, M., Vanholder, R., Sever, M. S., Cruz, D., Jaber, B., Lameire, N. H., Lombardi, R., Lewington, A., Feehally, J., Finkelstein, F., Levin, N., Pannu, N., ... Remuzzi, G. (2015). International Society of Nephrology's 0by25 initiative for acute kidney injury (zero preventable deaths by 2025): A human rights case for nephrology. The Lancet, 385(9987), 2616-2643. https://doi.org/10.1016/S0140-6736(15)60126-X

@article{469fa493049e4b5ab38492020094f94e,

title = "International Society of Nephrology's 0by25 initiative for acute kidney injury (zero preventable deaths by 2025): A human rights case for nephrology",

author = "Mehta, \{Ravindra L.\} and Jorge Cerd{\'a} and Burdmann, \{Emmanuel A.\} and Marcello Tonelli and Guillermo Garc{\'i}a-Garc{\'i}a and Vivekanand Jha and Paweena Susantitaphong and Michael Rocco and Raymond Vanholder and Sever, \{Mehmet Sukru\} and Dinna Cruz and Bertrand Jaber and Lameire, \{Norbert H.\} and Ra{\'u}l Lombardi and Andrew Lewington and John Feehally and Fredric Finkelstein and Nathan Levin and Neesh Pannu and Bernadette Thomas and Eliah Aronoff-Spencer and Giuseppe Remuzzi",

note = "Funding Information: We thank Arjan van der Tol, Valerie Luyckx, and Noel Gibney for their wonderful work with the RDRTF/ISN (Renal Disaster Relief Task Force of the International Society of Nephrology) for providing the epidemiologic earthquake data; and Sue Lahey and Ann Marie L'Hommedieu from the Schaffer Library, Albany Medical College (NY, USA) for their invaluable help in the literature search. The International Society of Nephrology (ISN) provided funding through unrestricted grants to the 0by25 initiative, gave logistic support for this study, and holds all copyrights on the data obtained through this study. Further support has been provided through unrestricted grants from Astute Medical (San Diego, CA, USA), Danone Nutricia Research (Palaiseau, France) and Bellco (Mirandola, Italy). Funding Information: Reductions in deaths from AKI will probably lead to an increase in patients who will have CKD and might convert to ESRD, needing chronic dialysis or transplantation. 202–205 Long-term RRT for ESRD will not be an option for patients in most LMICs; however, there is much goodwill in the international nephrology community to assist in the development of AKI programmes for peritoneal dialysis. Lessons learned in Tanzania (Moshi) at the Kilimanjaro Christian Medical Centre, 206 as well as anecdotal initiatives in other sub-Saharan countries and in Asia, show that, in a setting of low resources, good results from peritoneal dialysis are possible and can have favourable outcomes in patients with AKI and also be an affordable dialysis method for patients with ESRD. The 0by25 programme builds on and would implement the Saving Young Lives project a partnership among ISN and the International Paediatric Nephrology Association, International Society of Peritoneal Dialysis, and Sustainable Kidney Care Foundations, already in place and initially funded and supported by the Recanati–Kaplan Foundation. We believe that improved knowledge, coupled with advances in technology and improvements in health care, will provide additional novel approaches for the management of chronic diseases. Some evidence suggests that appropriate management of CKD and its risk factors, to prevent disease progression to ESRD in resource-poor settings, is affordable with the use of cheap drugs and simple organisation. 207 Our proposed strategy will be sustainable because it focuses not only on immediate improvement of care but also on developing education and training programmes for local delivery of care, and enables progress to be measured and challenged. ",

year = "2015",

month = jun,

day = "27",

doi = "10.1016/S0140-6736(15)60126-X",

language = "English",

volume = "385",

pages = "2616--2643",

journal = "The Lancet",

issn = "0140-6736",

publisher = "Elsevier B.V.",

number = "9987",

}

Mehta, RL, Cerdá, J, Burdmann, EA, Tonelli, M, García-García, G, Jha, V, Susantitaphong, P, Rocco, M, Vanholder, R, Sever, MS, Cruz, D, Jaber, B, Lameire, NH, Lombardi, R, Lewington, A, Feehally, J, Finkelstein, F, Levin, N, Pannu, N, Thomas, B, Aronoff-Spencer, E & Remuzzi, G 2015, 'International Society of Nephrology's 0by25 initiative for acute kidney injury (zero preventable deaths by 2025): A human rights case for nephrology', The Lancet, vol. 385, no. 9987, pp. 2616-2643. https://doi.org/10.1016/S0140-6736(15)60126-X

TY - JOUR

T1 - International Society of Nephrology's 0by25 initiative for acute kidney injury (zero preventable deaths by 2025)

T2 - A human rights case for nephrology

AU - Mehta, Ravindra L.

AU - Cerdá, Jorge

AU - Burdmann, Emmanuel A.

AU - Tonelli, Marcello

AU - García-García, Guillermo

AU - Jha, Vivekanand

AU - Susantitaphong, Paweena

AU - Rocco, Michael

AU - Vanholder, Raymond

AU - Sever, Mehmet Sukru

AU - Cruz, Dinna

AU - Jaber, Bertrand

AU - Lameire, Norbert H.

AU - Lombardi, Raúl

AU - Lewington, Andrew

AU - Feehally, John

AU - Finkelstein, Fredric

AU - Levin, Nathan

AU - Pannu, Neesh

AU - Thomas, Bernadette

AU - Aronoff-Spencer, Eliah

AU - Remuzzi, Giuseppe

N1 - Funding Information: We thank Arjan van der Tol, Valerie Luyckx, and Noel Gibney for their wonderful work with the RDRTF/ISN (Renal Disaster Relief Task Force of the International Society of Nephrology) for providing the epidemiologic earthquake data; and Sue Lahey and Ann Marie L'Hommedieu from the Schaffer Library, Albany Medical College (NY, USA) for their invaluable help in the literature search. The International Society of Nephrology (ISN) provided funding through unrestricted grants to the 0by25 initiative, gave logistic support for this study, and holds all copyrights on the data obtained through this study. Further support has been provided through unrestricted grants from Astute Medical (San Diego, CA, USA), Danone Nutricia Research (Palaiseau, France) and Bellco (Mirandola, Italy). Funding Information: Reductions in deaths from AKI will probably lead to an increase in patients who will have CKD and might convert to ESRD, needing chronic dialysis or transplantation. 202–205 Long-term RRT for ESRD will not be an option for patients in most LMICs; however, there is much goodwill in the international nephrology community to assist in the development of AKI programmes for peritoneal dialysis. Lessons learned in Tanzania (Moshi) at the Kilimanjaro Christian Medical Centre, 206 as well as anecdotal initiatives in other sub-Saharan countries and in Asia, show that, in a setting of low resources, good results from peritoneal dialysis are possible and can have favourable outcomes in patients with AKI and also be an affordable dialysis method for patients with ESRD. The 0by25 programme builds on and would implement the Saving Young Lives project a partnership among ISN and the International Paediatric Nephrology Association, International Society of Peritoneal Dialysis, and Sustainable Kidney Care Foundations, already in place and initially funded and supported by the Recanati–Kaplan Foundation. We believe that improved knowledge, coupled with advances in technology and improvements in health care, will provide additional novel approaches for the management of chronic diseases. Some evidence suggests that appropriate management of CKD and its risk factors, to prevent disease progression to ESRD in resource-poor settings, is affordable with the use of cheap drugs and simple organisation. 207 Our proposed strategy will be sustainable because it focuses not only on immediate improvement of care but also on developing education and training programmes for local delivery of care, and enables progress to be measured and challenged.

PY - 2015/6/27

Y1 - 2015/6/27

UR - https://www.scopus.com/pages/publications/84937201762

U2 - 10.1016/S0140-6736(15)60126-X

DO - 10.1016/S0140-6736(15)60126-X

M3 - Review article

C2 - 25777661

AN - SCOPUS:84937201762

SN - 0140-6736

VL - 385

SP - 2616

EP - 2643

JO - The Lancet

JF - The Lancet

IS - 9987

ER -