Abstract
To the Editor: The article by Kovacs et al. on interleukin-2 therapy in patients with human immunodeficiency virus (HIV) infection (March 2 issue)1 highlights the dilemma that this disease poses: how to get rid of a virus whose replication is enhanced by activation of the immune system. The increase in the HIV RNA level after an infusion of interleukin-2 was most consistent in patients with CD4 counts of 200 or fewer cells per cubic millimeter. In this group, interleukin-2 was associated with “few immunologic improvements, and substantial toxic effects,” but increased levels of HIV RNA were also observed in patients.
Original language | English |
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Pages (from-to) | 192-193 |
Number of pages | 2 |
Journal | New England Journal of Medicine |
Volume | 333 |
Issue number | 3 |
DOIs | |
State | Published - 20 Jul 1995 |
Externally published | Yes |