Innate immune cells in the tumor microenvironment

Ming O. Li, Natalie Wolf, David H. Raulet, Leila Akkari, Mikael J. Pittet, Paulo C. Rodriguez, Rosandra N. Kaplan, Ariel Munitz, Zemin Zhang, Sijin Cheng, Nina Bhardwaj

Research output: Contribution to journalArticlepeer-review

54 Scopus citations


The tumor immune microenvironment (TIME) is a complex ecosystem that contains adaptive and innate immune cells that have tumor-promoting and anti-tumor effects. There is still much to learn about the diversity, plasticity, and functions of innate immune cells in the TIME and their roles in determining the response to immunotherapies. Experts discuss recent advances in our understanding of their biology in cancer as well as outstanding questions and potential therapeutic avenues.

Original languageEnglish
Pages (from-to)725-729
Number of pages5
JournalCancer Cell
Issue number6
StatePublished - 14 Jun 2021


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