Innate and adaptive immunity: The Yin and Yang of celiac disease

Bana Jabri, Donald D. Kasarda, Peter H.R. Green

Research output: Contribution to journalReview articlepeer-review

106 Scopus citations

Abstract

Celiac disease is a multigenetic complex inflammatory disorder with an autoimmune component, induced by gluten, a protein found in wheat. It is a unique human disease model to dissect the innate and adaptive immune mechanisms underlying T-cell-mediated tissue destruction and the development of T-cell lymphoma in conditions of chronic T-cell activation.

Original languageEnglish
Pages (from-to)219-231
Number of pages13
JournalImmunological Reviews
Volume206
DOIs
StatePublished - Aug 2005
Externally publishedYes

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