Initial presentation of pheochromocytoma with takotsubo cardiomyopathy: A brief review of literature

Karthik R. Gujja, Ahmed F. Aslam, Vladimir Privman, Furqan Tejani, Balendu Vasavada

Research output: Contribution to journalArticlepeer-review

31 Scopus citations


Takotsubo cardiomyopathy, or transient left ventricular apical ballooning or broken heart syndrome, is characterized by excessive sympathetic stimulation induced acute coronary vasospasm. A 46-year-old female presented with polyuria and polydypsia and was diagnosed with new-onset diabetes mellitus, treated with insulin and intravenous fluids. During the hospital stay, she complained of an episode of left-sided chest pain and had mildly elevated cardiac enzymes. EKG showed new ST-segment elevation in V2, V3 leads without reciprocal changes. Her coronary angiogram showed no significant coronary artery stenosis, but severe systolic dysfunction and akinesis of the mid-anterior, anteroapical, mid-inferior and inferoapical segments. Further workup was negative except for plasma metanephrine being elevated. MRI of the abdomen showed a right adrenal mass consistent with pheochromocytoma. Surgical resection of the adrenal mass showed evidence of pheochromocytoma and the patient's symptoms were resolved.

Original languageEnglish
Pages (from-to)49-52
Number of pages4
JournalJournal of Cardiovascular Medicine
Issue number1
StatePublished - Jan 2010
Externally publishedYes


  • Acute ST elevation
  • Direct myocyte injury
  • Excessive catecholamine release
  • Microvascular spasm
  • Myocardial stunning
  • Pheochromocytoma
  • Progressive T wave inversion
  • Stress-induced cardiomyopathy
  • Takotsubo cardiomyopathy


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