Inhibition of rat and human cytochrome P4502E1 catalytic activity and reactive oxygen radical formation by nitric oxide

Medicine & Life Sciences

• Cytochromes 93%
• Nitric Oxide 66%
• Reactive Oxygen Species 65%
• 1-hydroxyethyl radical 18%
• Ethanol 15%
• Superoxides 13%
• Protein Isoforms 11%
• Nitric Oxide Donors 10%
• Heme 10%
• Carbon Monoxide 9%
• spermine nitric oxide complex 7%
• glycosylated-nitric oxide complex hemoglobin A 7%
• 4-nitrophenol 6%
• pyrazole 6%
• Oxygen 6%
• Dimethylnitrosamine 6%
• NADPH-Ferrihemoprotein Reductase 6%
• Peroxynitrous Acid 5%
• NADPH Oxidases 5%
• Liver Microsomes 5%
• Microsomes 5%
• NADP 4%
• Hep G2 Cells 4%
• Cytochrome P-450 Enzyme System 4%
• Catalase 4%
• Lipid Peroxidation 4%
• Superoxide Dismutase 4%
• Epitopes 3%
• Iron 3%
• Western Blotting 3%
• Cell Line 2%
• Enzymes 2%

Chemical Compounds

• Oxygen Radical 100%
• Nitric Oxide 77%
• Cytochrome 71%
• Nitric Oxide Donor 12%
• Ethanol 11%
• Superoxide 8%
• Peroxynitrite 5%
• Spermine 5%
• Cytochrome P450 4%
• Pyrazole 4%
• Epitope 4%
• Dioxygen 4%
• Hemoglobin 4%
• Lipid 2%
• Donor 2%
• Oxide 2%
• Oxidation Reaction 1%