Inhibition of Acanthamoeba species by Pseudomonas aeruginosa: Rationale for their selective exclusion in corneal ulcers and contact lens care systems

M. N. Qureshi; A. A. Perez; R. M. Madayag; E. J. Bottone

doi:10.1128/jcm.31.7.1908-1910.1993

Inhibition of Acanthamoeba species by Pseudomonas aeruginosa: Rationale for their selective exclusion in corneal ulcers and contact lens care systems

M. N. Qureshi
, A. A. Perez
, R. M. Madayag
, E. J. Bottone

Icahn School of Medicine at Mount Sinai

Research output: Contribution to journal › Comment/debate

37 Scopus citations

Abstract

Cocultivation of Acanthamoeba castellani and Acanthamoeba polyphaga with live Pseudomonas aeruginosa and with broth filtrates of P. aeruginosa proved equally lethal to the Acanthamoeba spp. The P. aeruginosa-induced amebicidal activity is apparently toxin mediated and has two operative modes: it can function through binding of P. aeruginosa to the ameba membrane and in the presence of one or more P. aeruginosa exoproducts.

Original language	English
Pages (from-to)	1908-1910
Number of pages	3
Journal	Journal of Clinical Microbiology
Volume	31
Issue number	7
DOIs	https://doi.org/10.1128/jcm.31.7.1908-1910.1993
State	Published - 1993

Access to Document

10.1128/jcm.31.7.1908-1910.1993

Cite this

@article{f094360a17114282badf14561879fc39,

title = "Inhibition of Acanthamoeba species by Pseudomonas aeruginosa: Rationale for their selective exclusion in corneal ulcers and contact lens care systems",

abstract = "Cocultivation of Acanthamoeba castellani and Acanthamoeba polyphaga with live Pseudomonas aeruginosa and with broth filtrates of P. aeruginosa proved equally lethal to the Acanthamoeba spp. The P. aeruginosa-induced amebicidal activity is apparently toxin mediated and has two operative modes: it can function through binding of P. aeruginosa to the ameba membrane and in the presence of one or more P. aeruginosa exoproducts.",

author = "Qureshi, \{M. N.\} and Perez, \{A. A.\} and Madayag, \{R. M.\} and Bottone, \{E. J.\}",

year = "1993",

doi = "10.1128/jcm.31.7.1908-1910.1993",

language = "English",

volume = "31",

pages = "1908--1910",

journal = "Journal of Clinical Microbiology",

issn = "0095-1137",

publisher = "American Society for Microbiology",

number = "7",

}

TY - JOUR

T1 - Inhibition of Acanthamoeba species by Pseudomonas aeruginosa

T2 - Rationale for their selective exclusion in corneal ulcers and contact lens care systems

AU - Qureshi, M. N.

AU - Perez, A. A.

AU - Madayag, R. M.

AU - Bottone, E. J.

PY - 1993

Y1 - 1993

N2 - Cocultivation of Acanthamoeba castellani and Acanthamoeba polyphaga with live Pseudomonas aeruginosa and with broth filtrates of P. aeruginosa proved equally lethal to the Acanthamoeba spp. The P. aeruginosa-induced amebicidal activity is apparently toxin mediated and has two operative modes: it can function through binding of P. aeruginosa to the ameba membrane and in the presence of one or more P. aeruginosa exoproducts.

AB - Cocultivation of Acanthamoeba castellani and Acanthamoeba polyphaga with live Pseudomonas aeruginosa and with broth filtrates of P. aeruginosa proved equally lethal to the Acanthamoeba spp. The P. aeruginosa-induced amebicidal activity is apparently toxin mediated and has two operative modes: it can function through binding of P. aeruginosa to the ameba membrane and in the presence of one or more P. aeruginosa exoproducts.

UR - https://www.scopus.com/pages/publications/0027235557

U2 - 10.1128/jcm.31.7.1908-1910.1993

DO - 10.1128/jcm.31.7.1908-1910.1993

M3 - Comment/debate

C2 - 8349772

AN - SCOPUS:0027235557

SN - 0095-1137

VL - 31

SP - 1908

EP - 1910

JO - Journal of Clinical Microbiology

JF - Journal of Clinical Microbiology

IS - 7

ER -

Inhibition of Acanthamoeba species by Pseudomonas aeruginosa: Rationale for their selective exclusion in corneal ulcers and contact lens care systems

Abstract

Access to Document

Fingerprint

Cite this