Influenza A Virus PB1-F2: A Small Protein with a Big Punch

Gina M. Conenello, Peter Palese

Research output: Contribution to journalShort surveypeer-review

19 Scopus citations


Virulence factors, such as the recently discovered PB1-F2, contribute to the pathogenesis and comorbidity of influenza A virus. In this issue of Cell Host & Microbe, McAuley et al. characterize the role of PB1-F2, including in the pandemic 1918 virus, in causing increased lung pathology and fatal pneumococcus infection in mice. This work sheds light on the mechanisms of pathogenicity during influenza A virus infections.

Original languageEnglish
Pages (from-to)207-209
Number of pages3
JournalCell Host and Microbe
Issue number4
StatePublished - 11 Oct 2007


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