TY - JOUR
T1 - Influenza A Virus PB1-F2
T2 - A Small Protein with a Big Punch
AU - Conenello, Gina M.
AU - Palese, Peter
PY - 2007/10/11
Y1 - 2007/10/11
N2 - Virulence factors, such as the recently discovered PB1-F2, contribute to the pathogenesis and comorbidity of influenza A virus. In this issue of Cell Host & Microbe, McAuley et al. characterize the role of PB1-F2, including in the pandemic 1918 virus, in causing increased lung pathology and fatal pneumococcus infection in mice. This work sheds light on the mechanisms of pathogenicity during influenza A virus infections.
AB - Virulence factors, such as the recently discovered PB1-F2, contribute to the pathogenesis and comorbidity of influenza A virus. In this issue of Cell Host & Microbe, McAuley et al. characterize the role of PB1-F2, including in the pandemic 1918 virus, in causing increased lung pathology and fatal pneumococcus infection in mice. This work sheds light on the mechanisms of pathogenicity during influenza A virus infections.
UR - http://www.scopus.com/inward/record.url?scp=34848897191&partnerID=8YFLogxK
U2 - 10.1016/j.chom.2007.09.010
DO - 10.1016/j.chom.2007.09.010
M3 - Short survey
C2 - 18005736
AN - SCOPUS:34848897191
SN - 1931-3128
VL - 2
SP - 207
EP - 209
JO - Cell Host and Microbe
JF - Cell Host and Microbe
IS - 4
ER -