Influence of thyroid hormone on estrogen metabolism in man

Jack Fishman; Leon Hellman; Barnett Zumoff; T. F. Gallagher

doi:10.1210/jcem-22-4-389

Influence of thyroid hormone on estrogen metabolism in man

Jack Fishman, Leon Hellman, Barnett Zumoff, T. F. Gallagher

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

Thyroid hormone materially influenced the metabolism of administered estradiol-16-C¹⁴ in vivo in human subjects. The same individuals were studied at two different levels of thyroid hormone. When thyroid hormone was elevated there was a sharp decrease in the fraction converted to estriol and an increase in the fraction converted to 2-methoxyestrone. There was relatively little change in estrone.

Original language	English
Pages (from-to)	389-392
Number of pages	4
Journal	Journal of Clinical Endocrinology and Metabolism
Volume	22
Issue number	4
DOIs	https://doi.org/10.1210/jcem-22-4-389
State	Published - Apr 1962
Externally published	Yes

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title = "Influence of thyroid hormone on estrogen metabolism in man",

abstract = "Thyroid hormone materially influenced the metabolism of administered estradiol-16-C14 in vivo in human subjects. The same individuals were studied at two different levels of thyroid hormone. When thyroid hormone was elevated there was a sharp decrease in the fraction converted to estriol and an increase in the fraction converted to 2-methoxyestrone. There was relatively little change in estrone.",

author = "Jack Fishman and Leon Hellman and Barnett Zumoff and Gallagher, {T. F.}",

year = "1962",

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doi = "10.1210/jcem-22-4-389",

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AU - Hellman, Leon

AU - Zumoff, Barnett

AU - Gallagher, T. F.

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N2 - Thyroid hormone materially influenced the metabolism of administered estradiol-16-C14 in vivo in human subjects. The same individuals were studied at two different levels of thyroid hormone. When thyroid hormone was elevated there was a sharp decrease in the fraction converted to estriol and an increase in the fraction converted to 2-methoxyestrone. There was relatively little change in estrone.

AB - Thyroid hormone materially influenced the metabolism of administered estradiol-16-C14 in vivo in human subjects. The same individuals were studied at two different levels of thyroid hormone. When thyroid hormone was elevated there was a sharp decrease in the fraction converted to estriol and an increase in the fraction converted to 2-methoxyestrone. There was relatively little change in estrone.

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DO - 10.1210/jcem-22-4-389

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AN - SCOPUS:0008460414

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SP - 389

EP - 392

JO - Journal of Clinical Endocrinology and Metabolism

JF - Journal of Clinical Endocrinology and Metabolism

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ER -

Influence of thyroid hormone on estrogen metabolism in man

Abstract

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