Inflammatory bowel disease and immune thrombocytopenic purpura: Is there a correlation?

Jusuf Zlatanic, Burton I. Korelitz, Nathaniel Wisch, Peter Kim, Michael Ammirati, Samuel Schwarz, Steven Gruenstein, Lewis Lipsey

Research output: Contribution to journalArticlepeer-review

41 Scopus citations

Abstract

Different hematologic abnormalities are often encountered in patients with inflammatory bowel disease. Among them anemia, leukocytosis, and thrombocytosis are commonly seen. Leukopenia and thrombocytopenia are observed mostly as a side effect of therapy, particularly with use of immunosuppressive drugs. Immune thrombocytopenic purpura is rarely reported in association with inflammatory bowel disease. We present two cases with combination of these entities along with a literature review and treatment options. Immune thrombocytopenic purpura in these patients presented as an extraintestinal manifestation of inflammatory bowel disease mediated by a disturbance of the immune system.

Original languageEnglish
Pages (from-to)2285-2288
Number of pages4
JournalAmerican Journal of Gastroenterology
Volume92
Issue number12 SUPPL.
StatePublished - Dec 1997
Externally publishedYes

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